HOTAIR and neoplasm: Furthermore, several cancer-promoting or tumor-suppressing lncRNAs, such as NEAT1, H19, NRON, LUCAT1, and HOTAIR, can be found not only in malignant cells but also in tumor-specific immune cells (Willingham et al., 2005; Barnes et al., 2013; Yao et al., 2018; Shin et al., 2019; Agarwal et al., 2020).