Among 30 PI3K/AKT/mTOR pathway-related genes, upregulated genes in cervical cancer were as follows: EIF4EBP1 (P<0.001), GSK3B (P<0.001), HRAS (P<0.001), KRAS (P<0.05), NRAS (P<0.001), PIK3CB (P<0.001), and PIK3R2 (P<0.001); downregulated genes included CDKN1B (P<0.001), FOXO1 (P<0.001), FOXO3 (P<0.001), GRB10 (P<0.001), FOXO4 (P<0.001), NOS3 (P<0.001), PIK3R1 (P<0.001), PTEN (P<0.001), TSC2 (P<0.001), ULK1 (P<0.001), ATG13 (P<0.05), RPTOR (P<0.05) and RICTOR (P<0.001). The gene discussed is NOS3; the disease is cervical cancer.