Whole exome sequencing focused on 60 genes causative of monogenic neurodegenerative diseases (APP, ATP1A3, CCNF, CHCHD10, CHCHD2, CHMP2B, COL4A1, CSF1R, CYLD, DCTN1, DNAJC13, DNMT1, FUS, GCH1, GRN, HNRNPA1, HNRNPA2B1, ITM2B, LRRK2, MAPT, MATR3, NOTCH3, PRKAR1B, PRNP, PSEN1, PSEN2, SERPINI1, SNCA, SNCB, SQSTM1, TARDBP, TBK1, TIA1, TMEM230, TUBA4A, VCP, VPS35, ATP13A2, DNAJC6, FBXO7, HTRA1, OPTN, PANK2, PARK2, PARK7, PINK1, PLA2G6, SPG11, SYNJ1, TH, TREM2, TYROBP, VPS13C, POLG, ATP6AP2, RAB39B, UBQLN2, GBA, APOE, PLCG2). The gene discussed is DNAJC6; the disease is neurodegenerative disease.