Whole exome sequencing focused on 60 genes causative of monogenic neurodegenerative diseases (APP, ATP1A3, CCNF, CHCHD10, CHCHD2, CHMP2B, COL4A1, CSF1R, CYLD, DCTN1, DNAJC13, DNMT1, FUS, GCH1, GRN, HNRNPA1, HNRNPA2B1, ITM2B, LRRK2, MAPT, MATR3, NOTCH3, PRKAR1B, PRNP, PSEN1, PSEN2, SERPINI1, SNCA, SNCB, SQSTM1, TARDBP, TBK1, TIA1, TMEM230, TUBA4A, VCP, VPS35, ATP13A2, DNAJC6, FBXO7, HTRA1, OPTN, PANK2, PARK2, PARK7, PINK1, PLA2G6, SPG11, SYNJ1, TH, TREM2, TYROBP, VPS13C, POLG, ATP6AP2, RAB39B, UBQLN2, GBA, APOE, PLCG2). This evidence concerns the gene PINK1 and neurodegenerative disease.