APOE and Alzheimer disease: Most recently, in a second genome‐wide association study in DLB including data from 2591 patients and 4027 controls, Chia et al.[62] identified five significant loci: three previously identified (APOE, SNCA, and GBA) and two new loci, one of which had been previously implicated in AD (BIN1)[63] and the other in PD (TMEM175).[64] Again, the authors reported “a notably different profile at the SNCA locus” in DLB and PD, suggesting that “the regulation of SNCA expression may be different” in the two diseases.