Using a library of 88 444 sgRNAs targeting the transcriptional start site of 14 701 lncRNA genes, and selecting with the chemotherapy drug cytarabine, they identified lncRNAs that led to hyperactivation of the GAS6/TAM pathway, a resistance mechanism in many cancers, highlighting the potential importance of lncRNAs in understanding cancer and drug resistance.[86]. Here, GAS6 is linked to cancer.