CTCF and hepatocellular carcinoma: Furthermore, we observed that 129 (33.4%) HCC‐specific genes in HepG2 and 286 (31.0%) HCC‐suppressed genes in THLE2 showed cell‐specific CTCF looping involving the gene promoters (Figure 4C), implying a correlation between CTCF looping on the promoter and differential gene expression.