CTCF and hepatocellular carcinoma: Specifically, 223 CTCF binding sites proximal to the promoter of 191 (49.5%) HCC‐specific genes showed higher binding intensity in HepG2 and 401 CTCF binding sites proximal to the promoter of 351 (38.0%) HCC‐suppressed genes had higher CTCF binding intensity in THLE2 cells (Figure 4A,B).