PDCD1 and neoplasm: Both SubQ and liver tumors in CSLT mice exhibited higher percentages of macrophages and lower fractions of Tregs and NK cells (Figure 2A), supporting that tumors growing in the liver not only affected leukocyte infiltration locally but also influenced the immune infiltration in distant tumor sites.[10, 11] Anti‐PD‐1 increased the percentage of tumor‐infiltrating CD8+ T cells and decreased macrophages and DCs in both SubQ and liver tumors, similar to the alterations in SubQ‐only mice.