With scRNA‐seq data on CD45+ immune cell populations of these mice, we compared our data with colorectal cancer (CRC) patients and revealed that most tumor‐infiltrating immune cell subsets were conserved with similar gene expression patterns.[14] The pivotal elements in TME including terminally Tex cells and immunosuppressive TAMs could reflect their equivalent functions in humans, providing insights into how liver metastases would possibly diminish responses to immunotherapy. The gene discussed is PTPRC; the disease is neoplasm.