CD14 and cancer: By comparison, Mono‐c03‐Vcan and Mono‐c04‐Ace were enriched in tumors (Figure S6D, Supporting Information) and similar to classical CD14hiCD16– and CD14+CD16hi monocytes in CRC patients, respectively (Figure S6C, Supporting Information).[14] Within the 5 macrophage clusters, only Macro‐c01‐Slc40a1 showed non‐cancer tissue preference, whereas the remaining clusters were enriched in tumors and thus denoted as TAMs (Figure S6B,D, Supporting Information).