PRF1 and colorectal carcinoma: Indeed, CD8‐c11‐Ccr7 exhibited higher stemness score (defined by the mean expression of Ccr7, Il7r, Sell, and Tcf7) and cytotoxicity score (defined by the mean expression of Ifng, Nkg7, Prf1, Ccl3, and Ccl4) than CD8‐c10‐Cd244 (Figure 2G), consistent with the previous study.[36] Survival analyses on TCGA CRC patients also revealed that the ratio of early and terminally Tex cells was related to better prognosis (Figure 2H).