KEGG analysis found that they were enriched in the AGE-RAGE signaling pathway in diabetic complications, coronavirus disease-COVID-19, rheumatoid arthritis, IL-17 signaling pathway, staphylococcus aureus infection, viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway and other pathways (Supplementary Table 9). Here, TNF is linked to rheumatoid arthritis.