Profiling phosphoprotein patterns in the blood and spleen of control, MT-, and MTGCSF−/−-bearing mice revealed that tumor-secreted GCSF led to a significant increase in pSTAT3 in cells associated with GCSFR expression, such as Neut/MDSCs and cMos (ref. 41; Fig. 2C and D). Here, CSF3 is linked to neoplasm.