NRXN1 and Delayed speech and language development: Cases 6 and 7 both had chr15q11.2 deletions that are associated with schizophrenia, attention deficit hyperactivity disorder (ADHD), and ASD.[65, 87, 88, 89] Case 1 had a NRXN1 deletion, which likewise is associated with a wide spectrum of developmental and neuropsychiatric disorders, including intellectual disability, speech delay, ASD, hypotonia, and schizophrenia.[90] We were interested in whether this rate of CNVs was higher than in ASD or control populations.