With respect to demographic features, for example, Blümcke et al. (1999) found patients with brain tumors with epilepsy and CD34 expression had younger age at seizure onset or at surgery and Vornetti et al. (2017) found CD34 expression in LEAT was significantly associated with a longer duration of epilepsy, which was similarly reported by Giulioni et al. (2019) who also reported that CD34 expression in LEAT appeared to be significantly related to older age at surgery, higher AED intake, and female sex by univariate analysis. This evidence concerns the gene CD34 and brain neoplasm.