Although some of studies reported the significant correlation of CD34 expression or BRAFV600E mutation in GG with tumor recurrence or progression (Lisievici et al., 2021), the extent of the surgical resection (or tumor location), instead of CD34 expression and BRAFV600E mutation, may play an important role of the tumor prognosis of low-grade GG (Chappé et al., 2013; Dahiya et al., 2013; Zaky et al., 2018; Wang et al., 2022). Here, CD34 is linked to neoplasm.