SOD1 and Dravet syndrome: The overexpression of SOD-1 gene in the 22.2–22.3 region of the long arm of chromosome 21 in individuals with DS (Donato, 2001; Netto et al., 2004) likely disturbs the steady-state biochemical balance of intracellular reactive oxygen species and increases the content of intracellular ROS, favoring enrichment of Prevotella.