For instance, higher levels of fibrinogen and CTGF were found in COVID-19 patients, and they serve as indictors for coagulation, fibrinolysis, and lung injury (Long et al., 2021; Sur et al., 2021; Laloglu and Alay, 2022), We discerned that these genes were also upregulated in CMs after infection, suggesting a similar pathologic progression in the CMs. Here, CCN2 is linked to infection.