LUM and renal cell carcinoma: A recent study combining scRNA-seq and cell line sequencing profile has identified the transcriptome signatures of RCC-specific CAFs, including COL1A1, COL1A2, COL5A1, COL16A1, elastin microfibril interfacer 1 (EMILIN1), lysyl oxidase-like 1 (LOXL1), and lumican (LUM) (Liu et al., 2020).