COL1A1 and renal cell carcinoma: RCC-associated ECM is more abundant, denser, and stiffer, with increased deposition of fibronectin (FN1), collagen 1 (COL1A1 and COL1A2), and collagen 6 (COL6A1, COL6A2, and COL6A3) (Bond et al., 2021).