Recently, in another study of an extensive literature review and standardized clinical validity assessment of a large number of genes, some of these meiotic prophase genes were shown to be associated with male infertility with ‘strong’ evidence (Tex11 and Tex15), with ‘moderate’ evidence (Sycp3), or with ‘limited’ evidence (Dmc1, Mei1, Meiob, Spo11, Syce1, and Tdrd9) (Oud et al., 2019). This evidence concerns the gene SYCP3 and male infertility.