ADAM8 and colonic neoplasm: In agreement, also other cancer types, such as breast cancer (Romagnoli et al., 2014; Conrad et al., 2018), lung cancer (Ishikawa et al., 2004), liver cancer (Zhang et al., 2013), pancreatic cancer (Valkovskaya et al., 2007), esophageal cancer (Chen et al., 2021), gastric cancer (Huang et al., 2015), glioblastoma (Dong et al., 2015; Schäfer et al., 2022) and colon cancer (Yang et al., 2014; Jin Q. et al., 2020) highlight a correlation between ADAM8 expression and cancer development and its malignant progression.