In that study we concluded that future lymphocyte studies on our MDD cohort should take more detailed parameters for premature immune aging into account, such as anti-cytomegalovirus (CMV) titers (as a sign of chronic CMV infection) and percentages of end-stage differentiated senescent CD4+T helper and CD8+T cytotoxic cells. The gene discussed is CD8A; the disease is cytomegalovirus infection.