PPARG and mycobacterial infectious disease: The increased control of mycobacterial infection by PPARγ inhibition was concomitant with an increase in TNFα synthesis and a decreased LDs biogenesis (Almeida et al., 2009; Rajaram et al., 2010), providing evidence that mycobacterial-induced PPARγ is an important mechanism in favoring mycobacterial growth in macrophages, at least partly through transcriptional regulation of inflammatory cytokines and lipid metabolism.