Interestingly, there were two CpGs with decreased 5-hmC levels and increased gene expression in astrocytoma, ependymoma, and glioneuronal/neuronal tumors: cg18280362 located in the promoter region of CWH43 and cg08278401 located in the promoter region of LRRC72. The gene discussed is CWH43; the disease is ependymoma.