The results revealed that AAR was positively associated with age, sex distribution, diabetic duration, SBP, HDL-C, apoA, fibrinogen, serum Cr, urinary ACR, VPT and prevalence of DPN, DN, hypertension, DFU, PAD, and negatively with BMI, smoking, DBP, TG, apoB, TyG, FBG, HbA1c, ALT, AST, TBIL, GGT, serum ALB, WBC, lymphocyte counts, eGFR, ABI, HSL, and prevalence of dyslipidemia, NAFLD and MetS (P<0.01 or P<0.05). The gene discussed is ALB; the disease is Hypertension.