The results revealed that AAR was positively associated with age, sex distribution, diabetic duration, SBP, HDL-C, apoA, fibrinogen, serum Cr, urinary ACR, VPT and prevalence of DPN, DN, hypertension, DFU, PAD, and negatively with BMI, smoking, DBP, TG, apoB, TyG, FBG, HbA1c, ALT, AST, TBIL, GGT, serum ALB, WBC, lymphocyte counts, eGFR, ABI, HSL, and prevalence of dyslipidemia, NAFLD and MetS (P<0.01 or P<0.05). This evidence concerns the gene APOB and metabolic syndrome.