In a study of 130 patients with CKD, serum Gal3 concentrations were directly correlated with C-reactive protein (CRP) concentrations and inversely correlated with eGFR, while higher serum Gal3 and CRP concentrations were associated with vascular reactivity index, a measure of endothelial dysfunction (Hsu et al., 2021). The gene discussed is LGALS3; the disease is endothelial dysfunction.