mTOR plays a central role in gene transcription, cell apoptosis, proliferation and differentiation, angiogenesis, tumor formation and development, and cell senescence through PI3K/Akt/mTOR signaling pathway (Hassan et al., 2013), and inhibiting this pathway could have therapeutic promises in leukemia disorders (Bertacchini et al., 2015). The gene discussed is AKT1; the disease is neoplasm.