YES1 and cancer: v-YES-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES1) is a non-receptor tyrosine kinase belonging to the SRC kinase family (SFK) that exerts critical functional control of cell survival, proliferation, adhesion, migration, invasion, cell death, and angiogenesis and regulates a number of cancer signaling pathway (Figure 2) (Garmendia et al., 2022).