Moreover, PTT reinforces tumor vascular permeability, allowing antitumor drugs delivery to deep tumor tissues and elevating the sensitivity of tumor cells resistant to chemotherapeutic treatments by suppressing the efflux transporters expression, including multidrug resistance-associated protein 1 (MDR-1) (Souslova and Averill-Bates, 2004). The gene discussed is ABCC1; the disease is neoplasm.