STAT3 and inflammatory bowel disease: Combined with previous reports, the activation of some classical pathways and abnormal expression of some cytokines promote carcinogenesis of IBD-CAC, including nuclear transcription factor-kappa B(NF-кB), Signal transducer and activator of transcription 3(STAT3), wingless/integrated (Wnt)/β-catenin, interleukin (IL)-6, IL-1β, and IL-17 (Hirano et al., 2020).