In the context of this study, CRS was implicated by critical care services (ICU) admission in four studies [8,9,14,16], mechanical ventilation in three studies [10,17,18], increased intubation rates in one study [13], elevated interleukin-6 in one study [11], clinical severity of COVID-19 in one study [15], and needed inpatient services in one study [12]. Here, IL6 is linked to COVID-19.