Other common genetic etiologies associated with EA/TEF include chromosomal disorders (trisomy 21, trisomy 18, trisomy 13), Feingold syndrome (MYCN), Fanconi anemia (multiple genes including FANCB, FANCC, FANCG, BRIP1) and other recurrent deletion and duplication syndromes [4,11]. Here, BRIP1 is linked to chromosomal disorder.