There were 24 risk factors available from these studies, including age, gender, marital status, smoking, height, BMI, waist circumference, duration of DM, fasting plasma glucose (FPG), HbA1c, total cholesterol (TC), TG, HDL-c, low density lipoprotein (LDL-c), SBP, DBP, C-reactive protein, eGFR, hypertension, DR, DKD, CVD, insulin, and statins. The gene discussed is CRP; the disease is diabetes mellitus.