The protein-protein interaction (PPI) network was illustrated based on the QTHX targets on NASH with the STRING database (Figure 1(B)) and the PPI core network (Figure 2(A)), was settled at 10 hub nodes, and 35 edges, which includes MAPK14, AKT1, FOX, HIF1A, RELA, JUN, TP53, MAPK3, CDKN1A, MAPK1. The gene discussed is JUN; the disease is metabolic dysfunction-associated steatohepatitis.