The univariate logistic regression analysis revealed that age, BMI, previous history of hypertension and diabetes mellitus, HR, BNP, Scr, FBG, TGs, and the TyG index ﻿were potential risk factors (univariate P < 0.05) for a mid/high SYNTAX score (SYNTAX score > 22, Table 2). The gene discussed is NPPB; the disease is hypertensive disorder.