CD274 and neoplasm: Furthermore, high PD-L1 expression (median split, CPS ≥ 5%) showed a better tumor response trend (ORR: 46.67% vs. 26.67%, p = 0.44, Fig. 6F), whereas no significant differences were observed in survival outcomes in the high PD-L1 expression group (median, PFS: high vs. low: 5.0 vs. 6.4 months, p = 0.81, Fig. 6G).