FGFR2 and Anxiety: Measures of anxiety-like behavior on the elevated plus maze was also shown to be altered in FGFR2 nKO mice in a comparable fashion to the FGFR2 cKO mice, with a small reduction in anxiety-like behavior: less time in the closed arms of the maze and more time in the center (Fig. 2G, ANOVA interaction: F (2,48) = 3.414, p = 0.04; p = 0.08, p = 0.048).