As shown in Fig. 6A and B, TRIM47 overexpression conferred Olaparib sensitive in triple-negative breast cancer cell lines, but inhibited TRIM47 conferred Olaparib resistance in triple-negative breast cancer cell lines, as determined by colony formation and Annexin V/PI assay, compared with vector-transformed cells. Here, ANXA5 is linked to triple-negative breast carcinoma.