This possibly due to the estrogen level in postmenopausal women decreases, which may cause an increase in lipoprotein lipase activity or a decrease in fat decomposition, leading to more severe abdominal fat accumulation [25], and then increased abdominal fat is associated with a series of metabolic abnormalities, such as insulin resistance and dyslipidemia, which may increase the level of uric acid in postmenopausal women [26]. Here, LPL is linked to Insulin resistance.