CEACAM5 and neoplasm: Apart from OS, univariate Cox regression analysis showed that T3 & T4 stage, N1 stage, N2 stage, M1 stage, III & IV pathological stage, lymphatic invasion, perineural invasion, tumor complete response after primary therapy, R1 & R2 residual tumor, CEA > 5 ng/mL, and KCNK9 expression were correlated with DSS (Table 3).