SOD1 and cancer: Furthermore, low doses of ionizing radiation induce antioxidant protective mechanisms through modulation of various antioxidant levels such as GSH and SOD, increasing anti-cancer activity, enhancing p53-related apoptosis of destroyed cells and precancerous cells apoptosis through reactive oxygen species (ROS)/reactive nitrogen species (RNS) and cytokine signaling, as well as inhibiting inflammation disease [94].