Also, chrysin has been found to reduce EAC tumor size through inhibiting VEGF and inflammatory molecules involved in angiogenesis [63], suppressing DNA topoisomerases [64], and histone deacetylase [65], as well as downregulating tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) [66]. Here, IL1B is linked to neoplasm.