TGFB1 and neoplasm: These can also be the cervicovaginal microbiome [18], immune cells in the tumor microenvironment such as macrophages and dendritic cells in association with naive T cells [19], pH of the microenvironment [20], and differential expression of oncogenic pathway proteins, such as EGFR1, Wnt/β-catenin, NF-κB, AKT, MMP3, TGF-β that may promote metastasis [21–26].