In a recent meta‐analysis examining the effect of exercise interventions (HIIT ~27% of all studies; MICT ~76%; MICT or HIIT in combination with resistance training ~22%) on circulating inflammatory markers in patients with CAD, neither significant reductions in TNF‐a, IL‐6 or IL‐8 concentrations, nor increases in IL‐10 were found; however, a reduction in C‐reactive protein (CRP) suggested diminished acute phase inflammation without changes in chronic inflammatory markers (Thompson et al., 2020). This evidence concerns the gene IL6 and coronary artery disorder.