Balmaña J., et al, carried out a registry of the results of hereditary cancer multigene panels from different laboratories, reporting contradictory interpretations in 26% of the interpreted variants, with greater frequency among the CHEK2 and ATM genes, followed by RAD51C, PALB2, BARD1, NBN, and BRIP1 (Balmaña et al., 2016). The gene discussed is PALB2; the disease is hereditary cancer.