A recent meta-analysis of children and adults with ADHD analyzed pro-inflammatory CRP, IL-1β, IL-6, IFN-α, TNF-α, and anti-inflammatory IL-10 and reported increased IL-6 and reduced TNF-α in children with ADHD compared to controls, while the other markers were not significantly different in ADHD patients [56]. This evidence concerns the gene IL1B and attention deficit-hyperactivity disorder.