CRP and Fever: In contrast, an observational study of 73 patients (ages 7–24) with Familial Mediterranean Fever, an autosomal recessive disorder characterized by recurrent attacks of fever, serositis, and articular pain and fed a diet supplemented with vitamin D, curcumin, and flaxseeds reported significant improvement in clinical presentation, cognitive functions, c-reactive protein, and subjective wellbeing over a 6-month period [31].