They found that in addition to the aging process and heavy cigarette smoking, MAFLD was an independent factor for COPD (OR 1.46, 95% CI 1.020–2.101, p = 0.0385); they also found that MAFLD was associated with COPD via low-grade inflammation evaluated by the CRP-to-albumin ratio. The gene discussed is ALB; the disease is chronic obstructive pulmonary disease.