GCKR-rs780094/A was positively associated with lnCRP levels after adjusting for age, gender, BMI, and NAFLD diagnosis (B = 0.098, p = 0.003), as well as with higher FLI values after adjusting for age, gender, and NAFLD diagnosis (B = 5.011, p = 0.007). Here, GCKR is linked to metabolic dysfunction-associated steatotic liver disease.