ABCG2 and immunodeficiency disease: It can be seen from Figure 4A,B that under the influence of alcohol, the total metabolic degree of the AF group was the highest compared with that of the other experimental groups and included ribosomes related to phagocyte defects, ABC transporters associated with hyperbilirubinemia, DNA replication associated with immunodeficiency, and homologous recombination related to defects in RecQ helicases.