Further, it is involved in the inhibition of PMA (phorbol 12-myristate 13-acetate)-induced MMP-1 (matrix metalloproteinases) and MMP-13 expression, initiation of tumor cells apoptosis, cell division arrest at various phases of the cell cycle, p53, caspase-3, Bcl2 and Bax expression modulation and retardation in levels of MPO (myeloperoxidase), and nitrite [14]. This evidence concerns the gene MPO and neoplasm.