Oxidative stress, inflammation, cytokine release, and transcription factor nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) can catalyze DNA methylation via the upregulation of DNA methyltransferases (DNMTs) in PCa [6,7,8,9,10,11,12,13,14]. This evidence concerns the gene NFKB1 and posterior cortical atrophy.