RNASE1 and cancer: The RNase A-NBC (RNase A modified with 4-nitrophenyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) benzyl carbonate) protein, having cytotoxic effects against cancer cells, showed enhanced toxicity against HeLa cells when compared to the free protein (Figure 12).