Huntington’s disease (HD) is characterized as a hereditary neurodegenerative disorder that causes the wasting of nerve cells caused by an abnormal expansion of the CAG trinucleotide repeat in exon 1 of the huntingtin gene (HTT), which leads to mutation of the HTT protein through various signaling mechanisms, resulting in neuronal death. The gene discussed is HTT; the disease is inherited neurodegenerative disorder.