BCL2 and neoplasm: Li et al. found that for cervical cancer He La cells, PCHPs could up-regulate the expression of apoptotic genes Bak, Cytc, Puma, and caspases-3 and related proteins, while down-regulating the expression of anti-apoptotic genes Bcl-2, Bcl-x L, and Bcl-2 proteins, thus promoting cancer cell apoptosis to exert anti-tumor effects [11].