Additionally, prior research has demonstrated that tea catechins affect cell membrane receptors and restrict the spread of breast cancer cells by lowering levels of neo-nourishing factors such as vascular endothelial growth factor (VEGF) and epidermal growth factor (EGFR) and blocking the chemical signaling and activation of protein transcription-3 (STAT-3) and nuclear factor kappa B (NF-κB) [101,102]. The gene discussed is VEGFA; the disease is breast cancer.