CXCR2 upregulation has been linked to a myriad of inflammatory disorders (such as asthma, chronic obstructive pulmonary disease, cystic fibrosis), autoimmune diseases (e.g., rheumatoid arthritis and psoriasis), and even neurodegenerative diseases (such as multiple sclerosis and Alzheimer’s disease) [8]. The gene discussed is CXCR2; the disease is neurodegenerative disease.